Services
RNA Forge provides off-the-shelf mRNAs, custom manufacturing, analytical services and technical development support for research and translational RNA programmes.
Technical capabilities
RNA Forge combines RNA manufacturing and analytical workflows to support material generation, process development and product understanding.
Defined mRNA options include enhanced green fluorescent protein (eGFP), NanoLuciferase (NanoLuc), firefly luciferase (FLuc) and CRISPR-associated protein 9 (Cas9) for assay development, method setup, screening and non-clinical research.
Custom RNA production and process development support for research and translational applications, quoted according to construct, amount, format and analytical requirements.
Advanced analytical workflows providing deeper insight into RNA quality, integrity and process performance.
Focused technical input on RNA manufacturing workflows, analytical planning and manufacturability considerations.
RNA manufacturing charges
Choose a defined capped + N1mΨ catalogue sequence, then select an off-the-shelf amount. Requirements outside the catalogue sequences, formats or batch sizes are scoped as custom RNA manufacturing.
Prices in GBP, excluding VAT. Final pricing and billing currency confirmed in your quotation. ECB reference rates.
Prices shown exclude VAT. Catalogue prices and custom quotations may vary with project scope, construct format, turnaround requirements and agreed deliverables. A written quotation confirms applicable taxes, delivery and turnaround before project start.
Batch documentation
Samples are supplied with a Certificate of Analysis generated from comprehensive characterisation of the production batch.
Bioanalytical charges
Begin with a selected method or combine complementary methods in a defined package. Bespoke programmes and larger sample sets are quoted separately.
Prices in GBP, excluding VAT. Final pricing and billing currency confirmed in your quotation. ECB reference rates.
Prices for single-sample analysis:
| Quality attribute | Method | Price* |
|---|---|---|
| RNA concentration | UV spectroscopy | — |
| HPLC | £1,000 | |
| RNA size/integrity | Fragment Analyser | £500 |
| HPLC | £300 | |
| Sequence identity | High resolution LC-MS | £2,000 |
| Residual NTPs | HPLC | £300 |
| Residual DNA | ddPCR | £1,500 |
| Residual protein | NanoOrange™ | £500 |
| dsRNA content | Dot blot | £700 |
| ELISA | £1,000 | |
| Lumit™ | £1,500 | |
| 5′ capping efficiency | High resolution LC-MS | £1,200 |
| Poly(A) tail length/heterogeneity | High resolution LC-MS | £1,200 |
| DNA template | High resolution LC-MS | £900 |
*Prices exclude VAT. Batch discounts are available.
Method selection, sample number and matrix can affect final scope. Custom mass spectrometry workflows and additional RNA characterisation services are available by quotation. A written quotation confirms the selected methods, sample plan, turnaround and deliverables.
Discuss a project
Tell us which material, analytical package or development support you need. Custom work is scoped and quoted before project start.